DPCstruct | MC32303

Metacluster Properties and Pfam Annotations

Number of structural domains346
Mean domain length (aa)119 ± 16 aa
Standard deviation of domain lengths15.60
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score83.05
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)27.58
Pfam Score99.58
Assigned Pfam label(s) CL0023- CL0188

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6P5W5C7 9-110 LPDCKITNLTTDWNSGVNLAALLDYCQPGLFPHWRSLDPSQSVRNCTNAMNLAQREFGVPKVLEPEYLASPWLDELSGMTYLSYFMK…
L8GGH8 5-119 QAALLAWAQRCTEGYKGVNITNFTSSWRDGLAFAALVHNHHPESFDYEPLVNGADALKRLEVAFEAAGKAGVPNLLDPEDVLVGPQP…
A0A0K0EEA2 152-292 None
H3B992 506-640 None
A0A2C9K361 207-330 None
A0A7M5WZY0 125-241 None
A0A3Q0JIR1 130-235 None
A0A553P5K7 89-209 None
A0A6P5W7I9 764-889 None
T1EIK6 3-102 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.