DPCstruct | MC32302

Metacluster Properties and Pfam Annotations

Number of structural domains200
Mean domain length (aa)172 ± 38 aa
Standard deviation of domain lengths37.68
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score79.45
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)18.76
Pfam Score88.64
Assigned Pfam label(s) PF05965- CL0489- PF05964- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6S8DHT5 58-212 KAKFPLEPEGGGRGASKIKLISAGSMKISNKYSQQYHNHKFLYPVGFHSVRLFDSVLDPNKQCGYSSFILEGEKGPLFRLAHEGGYP…
L8GFL6 11-178 LLLPVARDEAGNPVLPITVKGTTILDLGEIVWDRPLFHSKQYLWPTGFKSTKRLPSISNPEEYTTYTSEIVDTGDDAPTFRVTPEDR…
A0A0K0EDE0 1902-2059 None
A0A7M5WI18 114-298 None
A0A397JS14 1-178 None
A0A397JKI0 1-94 None
A0A1U8EPY8 1-159 None
A0A0Q9XHM3 2-149 None
A0A1R0H742 312-510 None
H3AZ42 280-526 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.