DPCstruct | MC323

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)135 ± 19 aa
Standard deviation of domain lengths18.83
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score87.57
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.86
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)31.30
Pfam Score100.00
Assigned Pfam label(s) CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A453BBT0 4-119 NFRVLKRDIPWETYMSTKLITSTCLQLLRRYDHKPESQRGPLLDEDGPSYVRVFLNILRSISKEETVEYVLALIDEMLAANPKRAAL…
A0A668U7J7 13-155 TNIIAAKAAEVRANQVNWQSYLQSQMISTEDCEFIKKFEVASSDQKQVILTNEGHQCAKTFLNLMAHISKEQTVQYILTLIDDTLQE…
A0A7R8X781 1-149 None
A0A7J0FVP6 1-152 None
A0A182T430 22-137 None
A0A815KBD8 24-194 None
A0A4U0VMB8 277-403 None
S4RQK2 2-104 None
A0A7S0DB20 23-142 None
A0A4Q2DLB0 10-157 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.