DPCstruct | MC32286

Metacluster Properties and Pfam Annotations

Number of structural domains148
Mean domain length (aa)181 ± 35 aa
Standard deviation of domain lengths34.96
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score83.59
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)20.97
Pfam Score97.98
Assigned Pfam label(s) CL0052- CL0126- CL0530- PF08718- PF02204

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
M4E2I4 2-141 DYVAKVEDLAKASSSVSTLVVMMERDIEANCVRKAGSHTRNLLRVKRGLDMVKALFEEIIASEGDNSLKDPASKSYDQVFRPHHGWV…
A0A287N362 9-164 TAVAEAFEELARGMEADGGELRLAPFGDTCALVSVLFNSLGIAFKFAESEYVTKVNDLIGASREYATLNDILDKDVENDSVKKQGSH…
F6GXJ5 8-140 None
A0A654HQW9 2-155 None
V7CX29 33-178 None
A0A6A6L0T3 393-590 None
A0A6G0X4D3 209-435 None
A0A2U1QH50 212-380 None
A0A5A9NB62 158-395 None
A0A1I8FHM7 355-545 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.