DPCstruct | MC32238

Metacluster Properties and Pfam Annotations

Number of structural domains225
Mean domain length (aa)161 ± 32 aa
Standard deviation of domain lengths31.97
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score71.24
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)24.02
Pfam Score99.67
Assigned Pfam label(s) PF20209- PF14214

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E2L812 3-134 VARVRHTAVFVRVATGGRKMKANAMAFESPIPKIYDILPPPKADIEEVLAILFTGPSAPTPEDFARTPLLVRRNAVKRALDWLVLNH…
A0A7D9E8W8 11-156 PRKFSFENSMIPSPQPVQLHGLTQVEEMLIARALPIMRVYIKPGGQRGYSGHCVNLPQNITELATSLPRYPRALSVILVKVKGKNNT…
A0A4S8MA36 63-233 None
A0A2V1CZB0 506-652 None
A0A146H3V4 250-461 None
M1WE44 33-186 None
A0A0G4HSP8 208-366 None
A0A284R8P7 441-657 None
A0A284RAN5 276-425 None
A0A819XUZ2 158-284 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.