DPCstruct | MC3221

Metacluster Properties and Pfam Annotations

Number of structural domains126
Mean domain length (aa)222 ± 51 aa
Standard deviation of domain lengths50.96
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score88.82
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)27.80
Pfam Score85.72
Assigned Pfam label(s) PF00032- CL0328- PF00421

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A699GR73 238-504 None
A0A4D6LVZ3 8-128 None
A0A524QMP9 32-293 None
A0A2H0LCM3 65-349 None
A0A7V4XR30 27-287 None
A0A850BS57 21-280 None
A0A0K8RP24 2-135 None
A0A399WP45 80-254 None
A0A3M2AIM6 16-217 None
A0A7Y8IVB6 7-289 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.