DPCstruct | MC3221

Metacluster Properties and Pfam Annotations

Number of structural domains126
Mean domain length (aa)222 ± 51 aa
Standard deviation of domain lengths50.96
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score88.82
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)27.80
Pfam Score85.72
Assigned Pfam label(s) PF00032- CL0328- PF00421

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H9U1R3 7-174 IDLPAPSNISAWWNFGSLLLLCLMAQILTGLFLAMHYTSDISTAFSSVAHICRDVNYGWTIRNLHANGASFFFICIYLHIGRGLYYG…
A0A7X2TT01 7-205 GITLFLFTMFTIQVLTGVLLLLYYRPSPAEAYESVQFIMTRVEYGWLVRSVHSWSANLVILAAFIHMFSVLFLDAYRKPRELTWLSG…
A0A5S9I7R4 2-143 None
A0A1F6RCG0 31-261 None
A0A4Q0P906 2-212 None
A0A090MNH0 26-290 None
A0A0R3UDB2 6-213 None
A0A7X3WDF1 47-251 None
A0A3A6Q1Q9 69-264 None
A0A849WWJ1 18-285 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.