DPCstruct | MC322

Metacluster Properties and Pfam Annotations

Number of structural domains5583
Mean domain length (aa)128 ± 30 aa
Standard deviation of domain lengths30.20
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score72.63
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.40
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)24.27
Pfam Score98.35
Assigned Pfam label(s) PF00057- CL0550- CL0263- PF16833- PF05794

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
S3CJD9 160-351 None
A0A0K8W8F2 172-313 None
A0A5E4QX89 116-255 None
A0A5E4QVQ3 5-132 None
A0A5E4QUT5 140-288 None
A0A5E4QQ52 651-771 None
A0A5E4QQ74 617-709 None
A0A5E4QPV4 235-355 None
A0A6A6Q9Z6 42-224 None
A0A067R5F3 965-1091 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.