DPCstruct | MC322

Metacluster Properties and Pfam Annotations

Number of structural domains5583
Mean domain length (aa)128 ± 30 aa
Standard deviation of domain lengths30.20
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score72.63
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.40
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)24.27
Pfam Score98.35
Assigned Pfam label(s) PF00057- CL0550- CL0263- PF16833- PF05794

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A068WH47 122-258 None
Q4CV53 301-479 None
M1CAM1 108-248 None
A0A0D2X2J1 5-157 None
A0A340YDT9 344-468 None
E4XD39 124-306 None
E4XD37 2-90 None
E4XB15 180-293 None
E4XAR0 18-124 None
Q4DAC6 1-223 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.