DPCstruct | MC32040

Metacluster Properties and Pfam Annotations

Number of structural domains535
Mean domain length (aa)291 ± 77 aa
Standard deviation of domain lengths77.48
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score80.12
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.39
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)15.51
Pfam Score79.51
Assigned Pfam label(s) CL0199- PF00122- CL0404

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A655CAJ5 18-302 KSLRLRYGNIDIAVNANGVSGDYFNVYGMSFREGNTFNAVQQQDRAQVVVLDANTRRQLFPNKANVVGEVVLAGNMPVIVIGVAEEK…
A0A6P1YC69 1-214 MGLRRIISLALIIVISFSSYMYLKEKYNPTAVEIRFRGDLRNEEFRKIKKMLYLNVYSINYSMKYRQHKLIMTTGMDTQIIDIPIIY…
A0A7C1DY67 26-295 None
A0A7D7L102 22-378 None
H1YBQ4 152-370 None
A0A2W6V755 16-298 None
A0A2E0UNM4 20-354 None
B1C3M6 7-335 None
A0A523E9Y2 167-382 None
A0A535A1R3 82-287 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.