DPCstruct | MC32005

Metacluster Properties and Pfam Annotations

Number of structural domains29
Mean domain length (aa)267 ± 60 aa
Standard deviation of domain lengths59.98
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score71.39
Mean fraction of residues predicted as intrinsically disordered0.37
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)25.10
Pfam Score100.00
Assigned Pfam label(s) PF10221

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0V0RRW8 65-342 HALVSRNGRLYVQSLQIGRSSYEMLPSIKNGPGTAVTDYRVNAFQQLIEDSLLKPGGPTIPKGTAEKHLIETTEYWPLNNGSSVLFA…
A0A6P9B1C5 1-206 MLSSHGGEIFLHVLSTSRSILEDPPSISEGCGGRVTDYRITDFGEFMRENRLAPFLEPRYKNDESLEVPLERAKDQLEKHTRYWPMI…
A0A212CCS4 272-511 None
A0A0K0DJ77 1-257 None
A0A0X3P352 2-175 None
A0A061RKW6 119-342 None
A0A2S2NR79 197-441 None
A0A484BBA6 286-555 None
S9WYZ6 143-340 None
A0A7I8XKE5 685-1029 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.