DPCstruct | MC32000

Metacluster Properties and Pfam Annotations

Number of structural domains7035
Mean domain length (aa)158 ± 32 aa
Standard deviation of domain lengths31.71
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score85.29
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)12.93
Pfam Score95.05
Assigned Pfam label(s) PF09621- CL0418- PF13862- CL0489- PF01016

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
M2T3W4 23-176 None
A0A7V5R332 23-207 None
A0A4Q3LUJ7 261-436 None
A0A4Q3L2N6 183-356 None
A0A4Q3KNW9 468-639 None
A0A5E4HGA5 217-368 None
A0A6N9HFE4 207-339 None
A0A2T7NXS2 626-794 None
A0A4Q9BAD1 75-234 None
A0A7C3TJ91 6-114 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.