DPCstruct | MC32000

Metacluster Properties and Pfam Annotations

Number of structural domains7035
Mean domain length (aa)158 ± 32 aa
Standard deviation of domain lengths31.71
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score85.29
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)12.93
Pfam Score95.05
Assigned Pfam label(s) PF09621- CL0418- PF13862- CL0489- PF01016

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H2J0S7 68-208 None
A0A067KUU9 187-348 None
A0A1I2DND9 15-176 None
A0A1I1Z8U1 58-200 None
A0A3A8SS90 2-119 None
A0A1M7I2U1 4-159 None
A0A147JUB4 25-191 None
A0A6I3KZC7 47-181 None
I3CGR5 132-281 None
A0A2R6EX47 2-140 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.