DPCstruct | MC32000

Metacluster Properties and Pfam Annotations

Number of structural domains7035
Mean domain length (aa)158 ± 32 aa
Standard deviation of domain lengths31.71
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score85.29
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)12.93
Pfam Score95.05
Assigned Pfam label(s) PF09621- CL0418- PF13862- CL0489- PF01016

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
U3BCE2 1-88 MIRKYNSNDLDSVLKIWLEASVKAHDFVSADFWESQVESMRNVYIPASEVFVYEIESKIVGFYALYENNLAAIFVFPAFQGQGIGKQL
A0A2I5K1P8 8-150 VTAPDVFALLQEHLKSMTMHSPPESIHALNADRLRQPDVTFWSARENGILLGCGALKELNSRHGEIKSMKTSPHHVRKGVANRILRH…
A0A1Q6YRZ4 20-199 None
A0A7V2V3G1 421-575 None
A0A7V3AFF1 107-259 None
A0A535W5L9 13-165 None
A0A1Y4HAH5 5-87 None
Q977W4 5-143 None
A0A7V2UA15 282-516 None
A0A3N0AWF4 18-160 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.