DPCstruct | MC31995

Metacluster Properties and Pfam Annotations

Number of structural domains255
Mean domain length (aa)270 ± 50 aa
Standard deviation of domain lengths49.62
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score78.85
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)18.07
Pfam Score74.62
Assigned Pfam label(s) CL0126- CL0700- PF20509

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
K2KKS9 12-288 EVTDRIIAELEAGRVPWVQPWGKAKAGVGLPRNAATERSYSGINILILWGAVIEKGYAAQHWLTFRQALALGGHVRKGERGTTVVYA…
A0A374BH29 5-248 DKYEVVKQAWFEINEHLRNNKQDYIEYLKFSAKMYKQPYSDAVLVYQQNRNATKIAEYKKWGRLGRYVRRGSHGVAVFGKNHTCRYL…
A0A3S4P3E2 808-1107 None
A0A6S6Y8Q9 7-286 None
A0A6S6XL05 12-314 None
A0A1H0F0I6 2-236 None
I0X6E9 12-277 None
A0A7Y3LK33 6-192 None
A0A2A4RRY9 12-293 None
A0A2V4ESU3 1-209 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.