DPCstruct | MC31974

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)111 ± 13 aa
Standard deviation of domain lengths13.12
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score82.26
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)42.33
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4X2KQR0 1-135 MHKRKYTGLGLRWREEKWEDEDEENAQLLLEALRVLDRLKNIACPFLEGLYITRPRTMKQFLCTPSICRLLILEWLFARLYPSFGVS…
A0A1A8CGC7 7-116 EEQVARQLYDALQAAACPLVQGLYLKEDDSMLELLCSPSELRTDILAWICSRIDPNVANSKAARSHDPHALTKEMAAFGHELMLIQA…
A0A6I8R0C5 3-97 None
B4DXP4 1-115 None
A0A667IF58 1-112 None
A0A7N4P978 2-100 None
A0A7J7R478 15-137 None
Q4T950 4-100 None
A0A1S3LGT3 77-205 None
A0A6J0CIH3 1-118 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.