DPCstruct | MC31921

Metacluster Properties and Pfam Annotations

Number of structural domains477
Mean domain length (aa)162 ± 29 aa
Standard deviation of domain lengths28.79
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score84.82
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.49
Mean intra-cluster sequence similarity (%)16.51
Pfam Score97.58
Assigned Pfam label(s) PF20182- CL0126- PF09856

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J9VKD1 3-130 DPEDKLESLGVHVVERDLSSIGVDGLYDADTHTVFVHDGLTPGQRRATLAHELAHAERGEGAAPSAWHEHKQERRADTKSARWLVGF…
A0A2T3ILT8 25-176 TPDQLIHVVQDKVNIGEDILCAIARIFNLRVEYMPLELEESGTLSYDKEVDQWLITINSLHHPKRQRFTFAHELAHFFLHRDSQYDF…
A0A0N0K1E4 5-134 None
K2DLC6 8-182 None
A0A7V6KXG2 10-185 None
A0A6I2YAT0 26-206 None
A0A1I4PLK5 8-168 None
A0A661F2E9 223-381 None
A0A6S6XL05 160-318 None
A0A2G9Z466 8-144 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.