DPCstruct | MC31916

Metacluster Properties and Pfam Annotations

Number of structural domains143
Mean domain length (aa)211 ± 47 aa
Standard deviation of domain lengths47.48
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score89.86
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)19.08
Pfam Score68.49
Assigned Pfam label(s) PF20737- CL0059- PF20736

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2E0WWS3 411-646 CFWCCVGTGMENPGRYGQFIYARDADGGLYVNLFVPSVLTVQDGLEIRQENNFPQQPRTKLTFSVENSTEWTLRIRHPWWTPAGDMA…
A0A6D0ELZ3 23-167 DDALFINLYVGNSMVFPVGDQELQLRISGNYPWQDQVTITITSPVPVEHTLALRLPDWCDAPQLTLNGETLQGEVRQGYLYLNRRWQ…
A0A286CAZ4 121-331 None
A0A8B3C739 506-731 None
A0A7C3U866 1-146 None
A0A564RUE1 151-365 None
A0A287XE75 45-199 None
A0A3D5W3C5 2-155 None
W0EV91 539-765 None
A0A6N2SBB1 129-400 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.