DPCstruct | MC31889

Metacluster Properties and Pfam Annotations

Number of structural domains327
Mean domain length (aa)253 ± 70 aa
Standard deviation of domain lengths70.45
Length coefficient of variation0.28
Mean AlphaFold2 pLDDT confidence score78.49
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)18.88
Pfam Score99.55
Assigned Pfam label(s) PF00079- PF00067- CL0016

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0C2MF69 5-258 IINNFTSNILNHLCASQNGNVAITGIGFYMLMAAIKFRVQGRSYDQLSRIIEHDFHQLYDPHTWIHTRTAKKWNFLRFLANAIPDMR…
A0A3Q7WMJ7 71-301 FKDSAKCSQAGRIHSEFGVLFSQINQPDSNYTLSMANRLYGTKAVVFHQGKSVFVEMMYQTGTYKLAFIKDPQMQVLELPYVNNKLS…
A0A2R3N122 144-434 None
A0A4Y2UCX3 62-319 None
A0A5P1F8G5 2-213 None
A0A445CBV1 70-386 None
A0A170NJK6 219-520 None
A0A447G2K4 206-520 None
A0A340Y259 240-450 None
A0A835HK11 571-905 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.