DPCstruct | MC31785

Metacluster Properties and Pfam Annotations

Number of structural domains117
Mean domain length (aa)182 ± 41 aa
Standard deviation of domain lengths41.48
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score85.70
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)24.13
Pfam Score98.75
Assigned Pfam label(s) CL0063- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A812QVY4 242-413 GAEVILVSGPVSQPDPESVTIIKTETARDMLDAVLDNLPVDVAVCAAAVADWRVDNEQGSKIKKDESGQVPALNFTENPDILKTISN…
A0A7W1FM12 16-209 DAVRFISVAASGATALQVKDCLHHQGLSADLLLGIDASPNAPAQRYVDRRGLESALRQWITVNPTGVVVMSAAVNDYEVAQVAIEQP…
T0D0S9 2-139 None
A0A7K0VRD9 8-154 None
A0A6I9JAP8 69-229 None
A0A835H3G1 307-526 None
A0A7M5XFK3 85-309 None
A0A067BWC4 123-336 None
A0A5M8P9G4 2-178 None
A0A832HCG9 194-403 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.