DPCstruct | MC31775

Metacluster Properties and Pfam Annotations

Number of structural domains163
Mean domain length (aa)208 ± 47 aa
Standard deviation of domain lengths47.05
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score78.36
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)15.02
Pfam Score92.86
Assigned Pfam label(s) CL0611- PF21738

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y1I2F8 710-890 DAAERKRFAGDAHEYLIEQVQFTGDESIPASVSSSTQKIRLAFNHPVKELIWVITPETSAAVDPKNGNMLFDFGQIAGVDYIQSAKL…
A0A6P8ZL18 81-296 ERIKLLDATLYIRKVAISPSVMLGHAQALEKSPAKYPVNRVDIKTVTITQGLRDKNLDNLFMNQLPQRIIIGFVDNRAFNGDYARNG…
V4AFY0 5-147 None
B0ELU8 177-421 None
V4BP68 5-237 None
V4C692 2-137 None
V4CBZ6 1-135 None
G0NY73 229-436 None
A0A6V7WCE9 406-612 None
A0A2G5UIE7 573-777 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.