DPCstruct | MC31729

Metacluster Properties and Pfam Annotations

Number of structural domains27
Mean domain length (aa)318 ± 28 aa
Standard deviation of domain lengths27.87
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score78.63
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)22.28
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H3H267 10-319 PTRLFSAVVDKKSCVSSNYCTGGSSPYNGTICTSTSSYQKDVAAVFGSNPYVIVEKYGSGKSCSAAALSSIGTYVADTKCHRSSSST…
A0A6A3IC37 24-351 GKGTPGSMPTVVSLYDSCSQPASSVIITRELECSLDDAQTCQSTGVVATNCTNYVSGSDTSGAISEAFGDHPHLIVEEYDPSAMYCG…
A0A6A4E5Z3 19-343 None
A0A833S8Q2 28-367 None
A0A6A4C0K1 294-605 None
A0A2P4YTD2 124-425 None
A0A662X4J0 13-334 None
H3H924 1-390 None
H3H266 345-613 None
H3H4D8 67-388 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.