DPCstruct | MC31692

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)253 ± 18 aa
Standard deviation of domain lengths17.86
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score85.07
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)43.45
Pfam Score90.28
Assigned Pfam label(s) PF00925- PF12471

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A094A771 161-406 GGSYSIYYALAVASKEIELDHKPDFTNTEPASNIGPFPQWADKEKIVSLDPLGHLAPWLFKNTMDSENIDIRPTIAITKARMNLPEL…
A0A0D2XBZ3 22-268 GGSYSIYYALAVASNELNADHRPDFTNTEPAANIGPFPQWGDPKKIVAMDPWGHLAPWLFKDTIEKDNVDIRPTIAITKAHMKLPEL…
A0A554IUP7 37-303 None
A0A5D3AKL5 688-942 None
D7FLZ3 64-368 None
A0A1Q9CWW2 195-419 None
A0A401KZ29 662-906 None
I8A6V4 4-273 None
A0A1E3H3M0 56-321 None
A0A2U3DR06 238-493 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.