DPCstruct | MC31677

Metacluster Properties and Pfam Annotations

Number of structural domains97
Mean domain length (aa)119 ± 18 aa
Standard deviation of domain lengths17.57
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score84.15
Mean fraction of residues predicted as intrinsically disordered0.43
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)31.65
Pfam Score96.88
Assigned Pfam label(s) PF00137- PF20114- PF00507

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V6QED6 192-307 SGYVPVAIFAALIVGFGVVSLAIAWLLRPSRPDIVKLMNYECGAEPIGPAWVRFPVGFYLVALVFIVFDALAVFLVPWLLVLKPLGL…
A0A3A4NNX8 7-126 AALIFLLAAIAFVAFNVLVPRLFRPIRPDQEKLSNYECGERPIGGPWIRFNIRFYIIAIIFLIFDVEVLFIIPWAVVYRRLYSELGM…
A0A368PE57 2-95 None
A0A445CQK6 363-476 None
A0A838SUF5 37-135 None
A0A2E3HWW1 8-126 None
A0A852YW63 2-91 None
A0A4S8I587 241-351 None
A0A562RW74 57-177 None
M6E9N7 125-254 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.