DPCstruct | MC31497

Metacluster Properties and Pfam Annotations

Number of structural domains146
Mean domain length (aa)295 ± 57 aa
Standard deviation of domain lengths56.59
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score87.07
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)17.08
Pfam Score51.91
Assigned Pfam label(s) PF05090- CL0213- CL0131

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
M4VUC1 16-331 SLVAFRIAAGLLALYDALIKFPHIRWLYSTDGYRDFSAEFFSRSLWIHQLIANLSLQQWQMLIGLQAIAGIFLIIGWRPKVWLVVWL…
Q9A359 3-222 LELARRLVEILLALALIQQSLEHLRGFRDERILFGARIVLAVLVLAGVAGPWPLVGLAGLSLLILHRFQGPYNGGSDRMGLLILWCL…
A0A2A3Z7T0 23-307 None
A0A7S4E654 57-333 None
A0A2E4HEW8 419-743 None
A0A2E5G114 26-303 None
A0A6I7YLS1 2-273 None
A0A7W8E600 5-228 None
A0A7I8CC30 64-427 None
U2HTZ3 189-456 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.