DPCstruct | MC31445

Metacluster Properties and Pfam Annotations

Number of structural domains62
Mean domain length (aa)184 ± 26 aa
Standard deviation of domain lengths25.91
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score85.66
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)34.93
Pfam Score84.56
Assigned Pfam label(s) CL0220- CL0013- PF00015

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Z2G5U1 111-292 LEDLLFHTVAEGQEKIPAHKFLTALKATGLRTGDPRLKECMDTLKETLRNTSDGVTLDRHLFKKCVQSNIVLLTQAFRKKFVIPDFQ…
T1IPF4 122-334 NVDDILFALFKNEENLVPVGKFLAALRATGLRKTDPRLRELMNNLKTVREQKFGEIGSAEALTLDKETFKSVILENIVLISRAFRGQ…
A0A1Q8FRS1 29-242 None
A0A6J8APP7 65-202 None
A0A2R7VR35 99-297 None
A0A3D3S5K7 5-144 None
A0A0S2EF40 68-258 None
A0A6P9A761 63-259 None
K7GYT5 2-209 None
A0A6P8GK46 105-287 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.