DPCstruct | MC31439

Metacluster Properties and Pfam Annotations

Number of structural domains31
Mean domain length (aa)167 ± 16 aa
Standard deviation of domain lengths15.99
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score80.04
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)44.64
Pfam Score91.54
Assigned Pfam label(s) CL0023- CL0357- CL0181

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Z2FTS8 1-166 MFSVGQESISTSPASTKGPGRRKSRFALCRRNKANGVKASTVHPSCTPQAAKAVSNKEQHSISYTLSRAQTVVVEYNHDGHTDMFQI…
A0A7S4E7U7 28-191 VYGQLVVLGYKEYRVEGSTWHPVGARNEKFALARRDEANGIRRARARVGEPRRPGEKRRSADASHSVTMSVAAGARGADGKPVARSQ…
A0A654H2D3 4-185 None
A0A7R9P9Z9 47-189 None
A0A7J7VJL7 25-193 None
A0A1I8G795 510-666 None
A0A834XKW6 112-276 None
A0A6S8UDS2 28-191 None
A0A5K3ERC3 3-186 None
A0A669CNP2 150-292 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.