DPCstruct | MC31420

Metacluster Properties and Pfam Annotations

Number of structural domains157
Mean domain length (aa)161 ± 35 aa
Standard deviation of domain lengths34.50
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score85.02
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)22.57
Pfam Score76.62
Assigned Pfam label(s) PF21754- CL0340- CL0063- CL0099- PF02887

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6Q2XQ20 196-367 MLSGETAKGDYPLEAVRTQHMIAREAEAAMFHRQVFEDLRRAAPHSTDPAEAIAIGAVEASFKILASAFIVLTNSGRSAHLISRYRP…
A0A2N1JEG5 942-1118 VMLSGETAKGMYPTEAVKMMAETTYIAEQTLAYQALFNEMRALTRVPTNTNETIALVAVSASLEQKAGAILLMSTSGNTARLVSKYK…
A0A7W1EQ94 104-273 None
A0A7C6P3H1 3-111 None
A0A6P4E2G1 2-106 None
A0A6P4EEM9 298-466 None
A0A7S2U9B4 1-122 None
A0A7C4I830 11-164 None
A0A287AQJ5 960-1136 None
A0A5J4ZAI5 397-560 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.