DPCstruct | MC31415

Metacluster Properties and Pfam Annotations

Number of structural domains64
Mean domain length (aa)120 ± 19 aa
Standard deviation of domain lengths19.12
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score79.57
Mean fraction of residues predicted as intrinsically disordered0.46
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)26.84
Pfam Score100.00
Assigned Pfam label(s) CL0123

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7D5BB23 13-108 RILPDAVGHDLRPDPMTATTPAEFMELLRRYRIWSGQMSYREMALRSGRTVAASTFCTALRRDQLPKQSLLRTIIEVCGGTLAEQQT…
A0A562DNJ0 1-116 MKVAEPTDSDGRPDPSAAGTAAEFVDALRRLKNWSGMGFRRLEQRAAATGQVLPRSTTTSALHRNTLPREDLIIALVRACGEDQDKV…
A0A347PU93 108-229 None
A0A4R2JJT8 1-112 None
A0A852UM14 113-239 None
A0A0M8YGZ1 69-235 None
A0A1H6DV98 1-120 None
A0A5M7C655 8-115 None
A0A1I3UPX5 16-139 None
A0A652L5J5 12-123 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.