DPCstruct | MC314

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)139 ± 9 aa
Standard deviation of domain lengths8.75
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score82.27
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)25.75
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
N9XV52 153-292 KEVTDIEKNEFMKRCYNDILGIFKSLLSKSEEINQNFSYELEEITARKAIIKTFVNGTLVTGLKIWLGSSMGMRENSICISSGNWIN…
A0A4V3BUR8 1-159 MKKDFDSIQKIEFQEKSFKDLSDIIRQNIDELQAIENVNGKILKSSAQEFEAILVNRNQIKSESTLNLNILKESNSSRFINRIDTSG…
A0A840A8A5 182-304 None
A0A3M5FL21 122-257 None
A0A355EWF5 1038-1175 None
A0A451A366 252-392 None
A0A6L8IPX8 337-474 None
A0A7X7CIS3 1-135 None
A0A6N2CPY2 100-239 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.