DPCstruct | MC31358

Metacluster Properties and Pfam Annotations

Number of structural domains49
Mean domain length (aa)140 ± 21 aa
Standard deviation of domain lengths21.40
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score91.45
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)39.92
Pfam Score95.83
Assigned Pfam label(s) PF20732- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Y5W6Z6 11-144 KTDDQTGAPVYALTRDCARVLPPAVHGAAAIVFAPTVSKDASDESFWFLTNVLGQTLQSASDNGLKYGVIDRPNPLERRRVEPMDLI…
A0A1E2SKM3 1-106 MLSDVDALLFDIQDVGVRFYTYIWTLYLAMEAAGEAGVEVIVLDRPNPLGDRMDGPVLEPALASFVGLREIPLRHGLTVGELATLFA…
A0A2N0BCM6 54-248 None
A0A2V5WTP7 95-218 None
A0A136N795 91-204 None
A0A816VWF4 69-194 None
M6GGS5 3-117 None
A0A2V7KLY1 287-417 None
I0XB76 139-285 None
A0A7J3ZBH4 46-177 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.