DPCstruct | MC31335

Metacluster Properties and Pfam Annotations

Number of structural domains803
Mean domain length (aa)326 ± 93 aa
Standard deviation of domain lengths93.46
Length coefficient of variation0.29
Mean AlphaFold2 pLDDT confidence score86.92
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)16.01
Pfam Score77.48
Assigned Pfam label(s) CL0023- CL0181- CL0277- CL0029- PF21307

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2K3LJ71 1-142 MKIRSGGHDYEGVSYVSKVPFFILDMFNLRSIDIDIDTESAWVQTGAQLGEVYYRIAEKSKIHAFPAGVCPTVGVGGHVSGGGYGNL…
A0A4D7CB51 7-327 VEAASAIVRVANEYRVPLVPQAGNTGLVLGGAPDASGGEVVVSVERMNRIRSVDADDFSLVAEAGCILTEVQDAAAAVDRLFPLSLG…
A0A316ZNR6 189-590 None
A0A212DNX6 2-300 None
A0A6U5H377 212-649 None
A0A317WZ55 580-799 None
A0A814VW64 76-335 None
A0A2B4ST37 177-610 None
A0A6J4SZH6 1-283 None
A0A5C6T890 309-586 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.