DPCstruct | MC31317

Metacluster Properties and Pfam Annotations

Number of structural domains81
Mean domain length (aa)78 ± 12 aa
Standard deviation of domain lengths12.19
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score89.04
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.86
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)39.70
Pfam Score97.96
Assigned Pfam label(s) CL0425- PF02580- CL0617

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A853QXL7 1-80 MIALIQRVTRADVRVGGRTTGEIGAGLLALVCAERGDTEAAADKLLAKLLGYRVFSDAAGKMNLPVSNIDGEGRAGGLLL
A0A1F3R7S1 2-72 KIVIQRVSQASVEINQQIKSKIDNGLLILLGIENDDTFEDVEWLCEKIASLRIFGDENGAMNLSVLEVKGL
A0A1A6A7L0 1-79 None
A0A072PST1 1-80 None
A0A1E4T396 252-338 None
A0A3M0J044 1-80 None
A0A834X9K3 240-330 None
A0A3R8VVH8 632-741 None
A0A395IKX6 1-80 None
A0A377DE62 1-59 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.