DPCstruct | MC31298

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)135 ± 9 aa
Standard deviation of domain lengths8.89
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score89.02
Mean fraction of residues predicted as intrinsically disordered0.15
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)30.16
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7X8JWL5 1-130 MLDFSAASGTGIELDNSVISSNAVQINGTNLTSSGYIVSRNNISFNVGNLRSANDTGIVICSSDGDININTSKAEIKGTLYAPNGTV…
A0A374E737 76-213 IFDKIDSAYFSGNNIDEYSQDYTLEEINININDPLEVEGNATLTGNININTALKAFEDVTLNGEVKNTNNSVIFSKYGDIVIDSQNV…
A0A645A8W2 67-209 None
A0A0K8J6R2 125-251 None
E4SFQ4 117-259 None
A0A374G2A1 21-133 None
A0A7X4IC96 929-1055 None
A0A1I6LDP9 94-233 None
E6UJK0 88-231 None
A0A373S820 112-256 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.