DPCstruct | MC3127

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)127 ± 5 aa
Standard deviation of domain lengths5.31
Length coefficient of variation0.04
Mean AlphaFold2 pLDDT confidence score92.16
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.91
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)39.27
Pfam Score89.29
Assigned Pfam label(s) CL0105- CL0475

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2S5TN52 330-453 ADTRAQAIEQLKNVLSQTRLNGISTNLDYAHSVISDERFEQMQIWTRLLDDFDYVPNVIEVLQAGTQSSIQDFPGRVGYWDIGVPPS…
A0A1F5L7D2 5-135 IIASGKDRATAIRKISLALEKPTVIGVEMNLRYLPQTMTWNAFTTGELTTNTFNRFPSQAEGVETIEAGSDTHIHVVPERQGLCHIG…
A0A2N6NK53 296-420 None
A0A485CW87 1-134 None
A0A485D142 1-124 None
A0A2P9HYH8 32-160 None
M2QVK2 1-124 None
U4UNC5 850-969 None
B5I525 151-274 None
A0A663ASB6 64-188 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.