DPCstruct | MC31243

Metacluster Properties and Pfam Annotations

Number of structural domains333
Mean domain length (aa)412 ± 79 aa
Standard deviation of domain lengths79.06
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score77.40
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.49
Mean intra-cluster sequence similarity (%)13.48
Pfam Score54.34
Assigned Pfam label(s) CL0532- PF11038- CL0144- PF11040- CL0001

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A812TW46 45-472 CASCAKGYAISDSSVLLCTRCPTKWWQQALQWLCMLGKHVLPFALAAKSALQGLDEKDRVQEEAKRSAVLINQLLSFATVTGGLLTV…
A0A2C5XGN8 195-583 FRYLPLIILLFSALAVVFAGVFSPWGATNIFHWTSNYGRDTDLLRLVTPGFGDCLQYIQFVVLTGGLSLSYPGFYQPVVSQAAWSAL…
A0A812YKD7 54-428 None
V5AEB6 63-389 None
V5A2D6 187-566 None
A0A7S0AT33 522-877 None
A0A7S0Z2F5 182-458 None
W4KM39 34-427 None
A0A2P6NZB6 850-1188 None
A0A2P6NJL5 655-1018 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.