DPCstruct | MC31158

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)145 ± 18 aa
Standard deviation of domain lengths17.60
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score91.87
Mean fraction of residues predicted as intrinsically disordered0.56
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)24.03
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A252A5H7 10-160 SSSSGVHLVSSDVSIGNGAVWTDTELGDGGELFVEDGGLAVNTLVDKGDLTVDAGGVASGVTVTGNWNENGYFEVDGGTIADLTVKK…
A0A6N8Q6B0 23-187 AGSLTVVTGSRAVDTIINANGKMDVYGKDVGTVLNSAGTQTIYASATSDKANIKGGKQTVYGLATEANIESGEQIVDGGSTEKTHIN…
A0A4V2BN80 11-140 None
A0A149T4U0 133-264 None
A0A3L4XCG5 51-187 None
A0A8B4PBI3 55-219 None
A0A376VEA4 3-129 None
A0A252C144 7-162 None
A0A0T9M807 413-541 None
A0A1Y3G1C5 4-171 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.