DPCstruct | MC31034

Metacluster Properties and Pfam Annotations

Number of structural domains43
Mean domain length (aa)125 ± 21 aa
Standard deviation of domain lengths20.92
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score89.79
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)40.64
Pfam Score75.56
Assigned Pfam label(s) PF02965- PF02310

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A376U070 21-150 NVAKEMERQGFTIPLLIGGATTSKTHTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHGRKKPRTP…
A0A800L7M4 2-104 VYVASEMERQKFEVPLLIGGATTSRKHTAVKIEEKYSSSVIHVIDASRCVGMVSKLLNPDHKKELVHKTKKEYKTIRETFYQNQQKL…
A0A0B1PH14 28-142 None
A0A1X7TBL3 67-197 None
A0A2K8U605 470-586 None
A0A0D2MET8 248-376 None
A0A378N3K3 50-201 None
G6C3S5 190-304 None
A0A7J6TWA5 249-360 None
A0A379AMY3 1-85 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.