DPCstruct | MC30560

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)73 ± 9 aa
Standard deviation of domain lengths8.90
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score79.51
Mean fraction of residues predicted as intrinsically disordered0.35
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)36.78
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
R5LDR0 70-134 VEKPKCKLVGEDGNIYNLMGIASRALKKNGLEEEAKEMFNKITTEAKSYNEALCIIMDYVDVTGE
K1RA84 52-119 FKKEIEKPLVPIIGADGNVFNLIGICSRALKTAGYPDKAKEMTDRITSSGSYDEALSIMCEYIEPVNQ
A0A448W9G9 40-128 None
A0A1V5GJ76 2-73 None
A0A6G7ZC87 1-79 None
A0A0S8FZH5 8-75 None
A0A1H7QA84 53-134 None
A0A372SKW2 470-539 None
A0A3E2VZK9 115-201 None
A0A372WI67 152-240 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.