DPCstruct | MC305

Metacluster Properties and Pfam Annotations

Number of structural domains398
Mean domain length (aa)197 ± 38 aa
Standard deviation of domain lengths38.19
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score85.04
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.49
Mean intra-cluster sequence similarity (%)16.93
Pfam Score99.22
Assigned Pfam label(s) CL0126- PF00067

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2D6K5Y3 14-234 FEKQEIIQLLIVTLFTGFIFTFRDWGIESLDAGLGFTHLVLAILLALIALFFRVSVQKITGFAFGFNSTFMLWWAGLIISLVLVFIS…
A0A6N9Y2R2 5-183 TVVVTVLYAALARRQLDLGPLGGYLVGLGFVISLLGSVLLHELGHALTARRYGIGVRGITLELLGGYTEMDRDAPSPRVELLISLAG…
A0A848WWR3 3-170 None
A0A847CV07 10-207 None
W7Z9P7 1-127 None
A0A2M8Q2R6 197-416 None
A0A2A2SKC5 11-212 None
A0A3S0JY39 89-243 None
A0A7W8QQK8 163-399 None
A0A4Q9VMJ0 289-518 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.