DPCstruct | MC30449

Metacluster Properties and Pfam Annotations

Number of structural domains63
Mean domain length (aa)237 ± 47 aa
Standard deviation of domain lengths47.08
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score77.00
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)21.41
Pfam Score100.00
Assigned Pfam label(s) PF02194

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A818Y3J6 53-273 PIYDKIKTAFIQSKLFIRISDLQNDSSSSLKKSKSSTERAPLTGISDIDEPLYELVDLFVRDYIEIWYKTQISSDESFIDDVKSGIY…
M2QX33 35-251 LSAPKPKPVSLARRLLFPQLPADAPLPPLLSHPGAVPLDVELYDFIALALRAFVNPWWTKITRYDREFLPAITGVLAHVLRTLETRA…
B0X352 53-308 None
A0A317WCC1 40-288 None
A0A1J8PSF3 2-311 None
A0A2A4JYB0 51-300 None
A0A6V7U4U5 96-334 None
R8BU33 4-213 None
A0A4W2FVX5 72-340 None
A0A364N161 114-351 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.