DPCstruct | MC3043

Metacluster Properties and Pfam Annotations

Number of structural domains65
Mean domain length (aa)87 ± 10 aa
Standard deviation of domain lengths9.95
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score76.59
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)49.04
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2Z7CZA2 256-342 MDNVGMAAMFESLVATGLKGFLGCPAVIHEAALLEFFANGSVRDGLVVSTVNEVSVEISEQLLAETFELPVEGLTDLLEIPKDLVFD
A0A2Z7B2I9 7-89 SRSHHIDFDSVFRFDDAEIVQMFESLVTTGLMEFLGCPSIFHESALIEFFANGSVRDDMVFSTISGIAVEISESVFSATFGLP
A0A2Z7C6I4 2-68 None
A0A2Z7C472 56-150 None
A0A2Z7C3N6 2-89 None
A0A2Z7C3H8 7-92 None
A0A2Z7C196 231-318 None
A0A2Z7BYU2 8-78 None
A0A2Z7BQL2 127-232 None
A0A2Z7BR68 7-98 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.