DPCstruct | MC30283

Metacluster Properties and Pfam Annotations

Number of structural domains69
Mean domain length (aa)519 ± 101 aa
Standard deviation of domain lengths101.21
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score78.78
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)19.85
Pfam Score69.19
Assigned Pfam label(s) PF02865- PF20979- PF09267- CL0220- CL0073

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A821RS44 53-548 TWLQREAQTLQQYRLDLSEKHQKTLQLLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDLLQTWCEKLAEIIWQNRQQIRRAEHL…
A0A1I8G044 399-937 AVSDSYDSDIRSAGASEMAMTLEDEKMAELSVLKAKFEKEPHELVRLMQACLMEESRLLARTAAAESQGPASGAAPKRPSSSDSALL…
A0A1E1MX08 42-678 None
A0A0D8XCM8 2-428 None
A0A3S1BMQ8 2-559 None
A0A2B4S7F2 386-781 None
A0A6I8PQY1 282-911 None
A0A835NJ91 101-796 None
A0A0G2JX93 378-1015 None
L8HD01 300-675 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.