DPCstruct | MC30023

Metacluster Properties and Pfam Annotations

Number of structural domains500
Mean domain length (aa)156 ± 26 aa
Standard deviation of domain lengths26.03
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score84.21
Mean fraction of residues predicted as intrinsically disordered0.35
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)16.83
Pfam Score85.40
Assigned Pfam label(s) PF07452- PF00080- PF07589- PF10099- PF19422

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q19AV7 3-151 RAVAVLRGDSLVKGTVTFEQADEKSPTTISWNISGHDANAQRGFHIHQFGDNTNGCTSAGPHYNPFSKNHGAPSDVDRHVGDLGNIT…
A0A3D0QIY7 17-174 AAAQHDMHKMEKGPIKAVAVVFPAKDKTVKGLITFTQTEEGVKVVAHLEGLAPGTHGFHVHEFGDCSAPDFMSAGGHFNPTQMAHGA…
A0A0C2JY29 104-261 None
A0A7S4SE32 24-162 None
A0A7S2MRD9 200-371 None
A0A061RLM2 44-186 None
A0A7Y1ZWE2 216-363 None
A0A7R9L057 83-216 None
A0A7Y3B6S0 129-290 None
A0A7S0MIV4 13-153 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.