DPCstruct | MC30020

Metacluster Properties and Pfam Annotations

Number of structural domains159
Mean domain length (aa)106 ± 19 aa
Standard deviation of domain lengths18.72
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score79.74
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)20.83
Pfam Score89.70
Assigned Pfam label(s) PF09404- PF18755- PF16135- CL0057

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7V5CCS9 2-65 NTRGQVAKVRADGTLIAGEAKGSIHQVGAALEHAPSCNGWTYWNFKRDGKMVSIDVLRQQIRAE
A0A3D0QBR1 17-109 KWTQKINTGTLKKRKPGLAGLLPANAQLQAIYKGKEYSATVDEQGRIELDGTLFNSPSAAATHVTKGPKDGWILWRYQDEGGTWLSI…
A0A3Q2U5U7 232-358 None
A0A2G8TDY2 121-218 None
A0A4S8QJ32 39-143 None
W5W3E5 23-96 None
A0A847KFK3 123-216 None
A0A495A5V9 2-90 None
A0A1J4RIL1 182-298 None
A0A1Q9SPC2 18-127 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.