DPCstruct | MC30005

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)143 ± 12 aa
Standard deviation of domain lengths11.85
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score86.68
Mean fraction of residues predicted as intrinsically disordered0.44
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)45.72
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6J2QZC5 197-346 MNIEREQVKENKQNRKHLKSTARIKAEKERIRVEEERKLENVRQLAEARQKLEERELLILERLKLEEEEERAVQLQRRKREEKGKVS…
A0A1A8MWF0 1-127 MKAEKEKLRLEEERRLERIQQLSEVKRKLEERELLIQARLKLEEEEEERAVQRQRSKIKEEEKDTRRYVEALRAQMKERLSLLKLEL…
A0A6F9D920 389-543 None
Q0P6D6 782-936 None
A0A3M0ITB6 1-155 None
H0XYU1 43-174 None
A0A3S1B535 318-453 None
A0A4Z2AWH8 281-416 None
H2Y652 2-146 None
A0A667X029 336-478 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.