DPCstruct | MC29998

Metacluster Properties and Pfam Annotations

Number of structural domains3522
Mean domain length (aa)228 ± 44 aa
Standard deviation of domain lengths43.71
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score81.17
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)12.83
Pfam Score97.41
Assigned Pfam label(s) PF19872- CL0041- PF20985- CL0052- CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5Y2S1Y7 9-185 None
A0A2W7AXT1 3-244 None
A0A811TL30 10-216 None
A0A287UVJ4 818-1075 None
A0A1Q3HBX8 150-365 None
A0A1Q3HUZ9 187-371 None
A0A7C4ETP8 27-285 None
A0A3L7RVZ4 914-1191 None
A0A662LSP3 944-1224 None
A0A662LTW9 368-616 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.