DPCstruct | MC29998

Metacluster Properties and Pfam Annotations

Number of structural domains3522
Mean domain length (aa)228 ± 44 aa
Standard deviation of domain lengths43.71
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score81.17
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)12.83
Pfam Score97.41
Assigned Pfam label(s) PF19872- CL0041- PF20985- CL0052- CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7K4CXC2 25-214 None
W3X2U9 52-300 None
A0A1W9VRX0 205-457 None
A0A3D1CRD6 22-218 None
A0A7C4U8I5 815-1049 None
A0A6M5YWD1 578-782 None
A0A257TNJ1 1-193 None
A0A183AUQ3 5-195 None
A0A2M8DN86 363-553 None
A0A7C2K0Z8 24-286 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.