DPCstruct | MC29998

Metacluster Properties and Pfam Annotations

Number of structural domains3522
Mean domain length (aa)228 ± 44 aa
Standard deviation of domain lengths43.71
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score81.17
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)12.83
Pfam Score97.41
Assigned Pfam label(s) PF19872- CL0041- PF20985- CL0052- CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0L0DGC3 366-650 None
W7UMF4 248-488 None
A0A2V7V439 8-291 None
A0A0C3NCI0 11-244 None
M5C026 4-231 None
A0A212DAT6 68-334 None
A0A816DUG1 6-216 None
A0A349GWI6 214-408 None
A0A2M6VTR3 452-691 None
A0A7C5PBS8 22-248 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.