DPCstruct | MC29998

Metacluster Properties and Pfam Annotations

Number of structural domains3522
Mean domain length (aa)228 ± 44 aa
Standard deviation of domain lengths43.71
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score81.17
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)12.83
Pfam Score97.41
Assigned Pfam label(s) PF19872- CL0041- PF20985- CL0052- CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y1Q6B3 151-379 None
A0A1F3BGX8 24-239 None
A0A1W1CMZ6 26-302 None
A0A1W1CZX6 11-252 None
A0A2T1DBF2 2-207 None
A0A024GAZ0 246-468 None
A0A1E9C5K8 242-484 None
A0A7V0R0Y7 6-239 None
A0A4Y6W1C7 166-415 None
A0A2D6N3D2 354-650 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.